Multiple studies show Nu.Q® NETs test could predict sepsis patients at risk of deteriorating
The symposium explored research findings from three large, independent studies carried out at centers of excellence in
Professor
"The findings of these studies, summarized in Volition's report, clearly and consistently show that an elevated level of circulating H3.1 nucleosomes in sepsis patients reflects a dysregulated immune response and is associated with an increased risk of mortality, renal failure, respiratory failure, multi-organ failure, and septic shock.
"As a physician, we now know that sepsis patients, with an elevated H3.1 level on admission to intensive care, are at greater risk of deteriorating and we need to act quickly.
"I believe that using the Nu.Q® NETs test to measure elevated H3.1 nucleosome levels as a "treatable trait" in sepsis management could be a game changer in modifying a patient's trajectory. Introducing Nu.Q® NETs into hospitals could lead to new ways of treating sepsis, improve patient survival and the quality of life of survivors."
Dr
"Nu.Q® NETs, Volition's nucleosome quantification technology, is a simple, low-cost, accessible test to detect diseases associated with NETosis. Although NETs play a critical role in our normal immune response, elevated levels of NETs can lead to tissue damage and in severe cases, sepsis, organ failure, and death.
"Being able to predict a sepsis patient's clinical course early, by using Nu.Q® NETs in clinical practice, could significantly enhance sepsis management, enabling physicians more time to intervene and improve patient outcomes."
Volition is currently seeking to commercialize Nu.Q® NETs and the findings from these latest studies, highlighted in the company's ESICM symposium report, will support ongoing licensing discussions with key industry stakeholders.
Download Volition's report, titled: 'Sepsis: a brighter hope for tomorrow' here.
About Volition
Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.
Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help diagnose and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early diagnosis and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life. For more information about Volition's technology go to: www.volition.com.
Volition's research and development activities are centered in
The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.
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