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About the company
Ionis Pharmaceuticals, Inc. is engaged in ribonucleic acid (RNA)-targeted therapeutics. The Company has five marketed medicines and a pipeline in neurology, cardiology, and other areas of high patient need. It has nine medicines in Phase III development and multiple additional medicines in early and mid-stage development. The Company’s products include SPINRAZA, QALSODY, WAINUA, TEGSEDI and WAYLIVRA. SPINRAZA is used for the treatment of patients with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. QALSODY is an antisense medicine that is used for the treatment of adult patients with superoxide dismutase 1 amyotrophic lateral sclerosis (SOD1-ALS), a rare, neurodegenerative disorder that causes progressive loss of motor neurons leading to death. WAINUA is a self-administered subcutaneous LIgand-Conjugated Antisense (LICA) medicine used for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (ATTRv-PN).
- Revenue in USD (TTM)803.07m
- Net income in USD-358.81m
- Incorporated1991
- Employees927.00
- LocationIonis Pharmaceuticals Inc2855 Gazelle CourtCARLSBAD 92010United StatesUSA
- Phone+1 (760) 931-9200
- Fax+1 (302) 655-5049
- Websitehttps://www.ionis.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rhythm Pharmaceuticals Inc | 112.53m | -261.57m | 3.63bn | 226.00 | -- | 323.37 | -- | 32.24 | -4.31 | -4.31 | 1.86 | 2.49 | 0.3136 | 1.18 | 6.65 | 497,920.30 | -72.15 | -47.21 | -90.85 | -52.84 | 88.61 | -- | -230.11 | -681.38 | 3.34 | -- | 0.417 | -- | 227.56 | -- | -1.97 | -- | -42.10 | -- |
| Alvotech SA | 393.92m | -441.45m | 3.75bn | 999.00 | -- | -- | -- | 9.52 | -1.90 | -1.90 | 1.56 | -1.29 | 0.3595 | 1.56 | 4.24 | 394,313.30 | -40.28 | -- | -47.87 | -- | 59.03 | -- | -112.07 | -- | 1.92 | -0.0519 | 1.41 | -- | 9.84 | -- | -7.43 | -- | -- | -- |
| Immunovant Inc | 0.00 | -323.01m | 3.90bn | 207.00 | -- | 8.66 | -- | -- | -2.21 | -2.21 | 0.00 | 3.06 | 0.00 | -- | -- | 0.00 | -79.97 | -- | -92.17 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -22.93 | -- | -- | -- |
| Ultragenyx Pharmaceutical Inc | 522.75m | -558.99m | 4.25bn | 1.28k | -- | 12.25 | -- | 8.13 | -6.46 | -6.46 | 6.02 | 3.76 | 0.3766 | 1.91 | 6.06 | 409,674.80 | -40.27 | -33.35 | -50.12 | -38.30 | 86.25 | 93.13 | -106.93 | -154.71 | 2.65 | -- | 0.00 | -- | 19.52 | 53.18 | 14.25 | -- | 62.91 | -- |
| Biohaven Ltd | 0.00 | -804.34m | 4.45bn | 239.00 | -- | 13.57 | -- | -- | -9.35 | -9.35 | 0.00 | 3.33 | 0.00 | -- | -- | 0.00 | -180.09 | -- | -236.99 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 28.43 | -- | -- | -- |
| Alkermes Plc | 1.51bn | 502.58m | 4.48bn | 2.10k | 9.39 | 3.47 | 8.26 | 2.98 | 2.95 | 1.96 | 8.83 | 7.99 | 0.6788 | 1.32 | 4.24 | 716,724.30 | 22.67 | 1.34 | 28.90 | 1.74 | 83.17 | 83.32 | 33.39 | 2.12 | 3.03 | -- | 0.1827 | 0.00 | 49.61 | 8.74 | 1,665.99 | -- | -7.10 | -- |
| Arcellx Inc | 155.82m | -40.42m | 4.72bn | 130.00 | -- | 9.75 | -- | 30.27 | -0.7196 | -0.7196 | 2.98 | 8.95 | 0.226 | -- | -- | 1,198,600.00 | -5.86 | -38.82 | -7.56 | -45.41 | -- | -- | -25.94 | -339.38 | -- | -- | 0.022 | -- | -- | -- | 62.53 | -- | 113.86 | -- |
| Crinetics Pharmaceuticals Inc | 1.04m | -277.91m | 5.09bn | 290.00 | -- | 5.53 | -- | 4,902.86 | -3.72 | -3.72 | 0.0139 | 10.30 | 0.0013 | -- | 0.1222 | 3,582.76 | -34.61 | -42.53 | -36.80 | -45.36 | -- | -- | -26,298.27 | -5,446.39 | -- | -- | 0.00 | -- | -15.28 | 10.57 | -30.88 | -- | 34.65 | -- |
| Krystal Biotech Inc | 241.52m | 52.37m | 5.24bn | 229.00 | 103.14 | 5.92 | 88.24 | 21.71 | 1.77 | 1.77 | 8.21 | 30.80 | 0.2725 | 1.51 | 4.53 | 1,054,664.00 | 5.91 | -11.50 | 6.33 | -12.01 | 92.55 | -- | 21.68 | -492.85 | 7.76 | -- | 0.00 | -- | -- | -- | 107.81 | -- | 39.49 | -- |
| Ionis Pharmaceuticals Inc | 803.07m | -358.81m | 5.36bn | 927.00 | -- | 8.09 | -- | 6.67 | -2.45 | -2.45 | 5.50 | 4.20 | 0.267 | 0.3864 | 10.02 | 866,306.40 | -11.93 | -6.30 | -13.52 | -7.44 | 98.70 | 98.75 | -44.68 | -21.23 | 8.82 | -- | 0.6587 | -- | 34.10 | 5.60 | -35.80 | -- | 11.83 | -- |
| TG Therapeutics Inc | 264.79m | -14.36m | 5.38bn | 319.00 | -- | 28.01 | -- | 20.31 | -0.1067 | -0.1067 | 1.74 | 1.23 | 0.5775 | 0.5234 | 3.42 | 1,002,992.00 | -3.13 | -62.87 | -3.91 | -80.06 | 88.32 | -- | -5.42 | -405.03 | 3.91 | 0.2097 | 0.5596 | -- | 8,290.02 | 333.86 | 106.39 | -- | -- | -- |
| Cytokinetics, Inc. | 3.22m | -576.40m | 5.63bn | 423.00 | -- | -- | -- | 1,747.67 | -5.39 | -5.39 | 0.0301 | -0.118 | 0.003 | -- | 2.35 | 7,609.93 | -52.96 | -43.14 | -57.95 | -47.22 | -- | -- | -17,906.24 | -540.47 | -- | -14.27 | 1.02 | -- | -92.04 | -24.89 | -35.30 | -- | 9.76 | -- |
| Viking Therapeutics Inc | 0.00 | -99.15m | 5.75bn | 33.00 | -- | 6.31 | -- | -- | -0.937 | -0.937 | 0.00 | 8.18 | 0.00 | -- | -- | 0.00 | -15.02 | -21.91 | -15.47 | -23.04 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.73 | -- | -- | -- |
| Nuvalent Inc | 0.00 | -224.29m | 6.05bn | 127.00 | -- | 5.87 | -- | -- | -3.48 | -3.48 | 0.00 | 15.81 | 0.00 | -- | -- | 0.00 | -27.79 | -- | -29.25 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -54.20 | -- | -- | -- |
| Blueprint Medicines Corp | 434.41m | -128.05m | 6.14bn | 638.00 | -- | 19.58 | -- | 14.13 | -2.11 | -2.11 | 6.92 | 4.93 | 0.3769 | 0.8954 | 8.11 | 663,227.50 | -11.11 | -29.92 | -13.84 | -34.06 | 97.01 | -- | -29.48 | -116.65 | 3.27 | -10.80 | 0.5525 | -- | 22.22 | 41.14 | 9.06 | -- | 4.85 | -- |
Data as of Nov 22 2024. Currency figures normalised to Ionis Pharmaceuticals Inc's reporting currency: US Dollar USD
61.16%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Fidelity Management & Research Co. LLCas of 30 Sep 2024 | 22.48m | 14.25% |
| The Vanguard Group, Inc.as of 30 Sep 2024 | 14.83m | 9.40% |
| T. Rowe Price Investment Management, Inc.as of 30 Sep 2024 | 14.17m | 8.98% |
| Wellington Management Co. LLPas of 30 Sep 2024 | 8.61m | 5.46% |
| BlackRock Fund Advisorsas of 30 Sep 2024 | 8.31m | 5.27% |
| Bellevue Asset Management AGas of 30 Sep 2024 | 7.87m | 4.99% |
| Capital Research & Management Co. (World Investors)as of 30 Sep 2024 | 7.83m | 4.96% |
| SSgA Funds Management, Inc.as of 30 Sep 2024 | 4.85m | 3.08% |
| T. Rowe Price Associates, Inc. (IM)as of 30 Sep 2024 | 4.06m | 2.58% |
| Tweedy, Browne Co. LLCas of 30 Sep 2024 | 3.45m | 2.19% |
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Data from 30 Sep 2024 - 30 Sep 2024Source: FactSet Research Systems Inc.
